Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma

Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma

The current study focuses on the development and evaluation of nano lipidic carriers (NLCs) for codelivery of sorafenib (SRF) and ganoderic acid (GA) therapy in order to treat hepatocellular carcinoma (HCC). The dual drug-loaded NLCs were prepared by hot microemulsion technique, where SRF and GA as...

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Bibliographic Details
Main Authors: Bin Wang, Lin Sun, Mingyun Wen, Youchun Tan, Waleed H. Almalki, Hanadi Katouah, Imran Kazmi, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Fahad A. Al-Abbasi, Majed Alrobaian, Khalid S. Alharbi, Sattam K. Alenezi, Adel F. Alghaith, Sarwar Beg, Mahfoozur Rahman
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Saudi Pharmaceutical Journal
Subjects:
Sorafenib
Nanolipdic carrier
Hepatocellular carcinoma
Antioxidants
Inflammatory markers
Nonhepatic parameters
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016421001201

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http://www.sciencedirect.com/science/article/pii/S1319016421001201

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