Erythrocyte-binding assays reveal higher binding of Plasmodium knowlesi Duffy binding protein to human Fya+/b+ erythrocytes than to Fya+/b- erythrocytes

Erythrocyte-binding assays reveal higher binding of Plasmodium knowlesi Duffy binding protein to human Fya+/b+ erythrocytes than to Fya+/b- erythrocytes

Abstract Background The merozoite of the zoonotic Plasmodium knowlesi invades human erythrocytes via the binding of its Duffy binding protein (PkDBPαII) to the Duffy antigen on the eythrocytes. The Duffy antigen has two immunologically distinct forms, Fya and Fyb. In this study, the erythrocyte-bind...

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Bibliographic Details
Main Authors: Mun Yik Fong, Fei Wen Cheong, Yee Ling Lau
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Parasites & Vectors
Subjects:
Plasmodium knowlesi
Duffy binding protein
Duffy antigen
Erythrocyte-binding assay
Online Access:http://link.springer.com/article/10.1186/s13071-018-3118-8

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http://link.springer.com/article/10.1186/s13071-018-3118-8

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