Is paromomycin an effective and safe treatment against cutaneous leishmaniasis? A meta-analysis of 14 randomized controlled trials.

BACKGROUND: High cost, poor compliance, and systemic toxicity have limited the use of pentavalent antimony compounds (SbV), the treatment of choice for cutaneous leishmaniasis (CL). Paromomycin (PR) has been developed as an alternative to SbV, but existing data are conflicting. METHODOLOGY/PRINCIPAL...

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Bibliographic Details
Main Authors: Dae Hyun Kim, Hye Jin Chung, Joachim Bleys, Reza F Ghohestani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2637543?pdf=render