Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

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"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision.  The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or e...

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Bibliographic Details
Main Authors: A Aleyasin, M Ghazanfari, M Houshmand
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-09-01
Series:Iranian Journal of Public Health
Subjects:
LHON
MTHFR
MTRR
Folate
Folic acid
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16647.pdf&manuscript_id=16647

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http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/16647.pdf&manuscript_id=16647

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