Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1.

Methylglyoxal (MG) is a highly reactive metabolite physiologically presented in all biological systems. The effects of MG on diabetes and hypertension have been long recognized. In the present study, we investigated the potential role of MG in obesity, one of the most important factors to cause meta...

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Bibliographic Details
Main Authors: Xuming Jia, Tuanjie Chang, Thomas W Wilson, Lingyun Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3351465?pdf=render