Specific Inhibitor of Matrix Metalloproteinase Decreases Tumor Invasiveness After Radiofrequency Ablation in Liver Tumor Animal Model

Specific Inhibitor of Matrix Metalloproteinase Decreases Tumor Invasiveness After Radiofrequency Ablation in Liver Tumor Animal Model

ObjectiveTo determine whether the specific inhibitor of matrix metalloproteinase (MMP)—batimastat (BB-94)—could decrease the progression of liver tumor after radiofrequency ablation (RFA) and achieve better therapeutic efficacy in an animal model.MethodsIn vitro experiments, the proliferation of H22...

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Bibliographic Details
Main Authors: An-Na Jiang, Jing-Tao Liu, Kun Zhao, Hao Wu, Song Wang, Kun Yan, Wei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
liver tumor
radiofrequency ablation
invasiveness
specific inhibitor
matrix metalloproteinase
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.561805/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.561805/full

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