Effects of Neuropeptides and Mechanical Loading on Bone Cell Resorption in Vitro

Effects of Neuropeptides and Mechanical Loading on Bone Cell Resorption in Vitro

Neuropeptides such as vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide (CGRP) are present in nerve fibers of bone tissues and have been suggested to potentially regulate bone remodeling. Oscillatory fluid flow (OFF)-induced shear stress is a potent signal in mechanotransducti...

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Bibliographic Details
Main Authors: Yeong-Min Yoo, Ji Hyun Kwag, Kyung Hwan Kim, Chi Hyun Kim
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
neuropeptides
mechanical loading
bone resorption
RANKL (receptor activator of nuclear factor kappa B (NF-κB) ligand)
OPG (osteoprotegerin)
Online Access:http://www.mdpi.com/1422-0067/15/4/5874

Internet

http://www.mdpi.com/1422-0067/15/4/5874

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