Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.

Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.

BACKGROUND: Studies on osteoclasts, the bone resorbing cells, have remained limited due to the lack of transgenic mice allowing the conditional knockout of genes in osteoclasts at any time during development or adulthood. METHODOLOGY/PRINCIPAL FINDING: We report here on the generation of transgenic...

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Bibliographic Details
Main Authors: Maria Arantzazu Sanchez-Fernandez, Silvia Sbacchi, Miguel Correa-Tapia, Ronald Naumann, Jennifer Klemm, Pierre Chambon, Samiya Al-Robaiy, Manfred Blessing, Bernard Hoflack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3356310?pdf=render

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http://europepmc.org/articles/PMC3356310?pdf=render

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