Combined EGFR and VEGFR versus single EGFR signaling pathways inhibition therapy for NSCLC: a systematic review and meta-analysis.

BACKGROUND: Lung cancer is a heterogeneous disease with multiple signaling pathways influencing tumor cell survival and proliferation, and it is likely that blocking only one of these pathways allows others to act as salvage or escape mechanisms for cancer cells. Whether combined inhibition therapy...

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Bibliographic Details
Main Authors: Xinji Zhang, Yesheng Li, Hui Li, Yingyi Qin, Chong Bai, Feng Xu, Tianyi Zhu, Jinfang Xu, Mengjie Wu, Chaoxiang Wang, Lixin Wei, Jia He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3420905?pdf=render