Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury.

Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury.

The search for new approaches to treatment and prevention of heart failure is a major challenge in medicine. The adenosine triphosphate-sensitive potassium (KATP) channel has been long associated with the ability to preserve myocardial function and viability under stress. High surface expression of...

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Bibliographic Details
Main Authors: Zhan Gao, Ana Sierra, Zhiyong Zhu, Siva Rama Krishna Koganti, Ekaterina Subbotina, Ankit Maheshwari, Mark E Anderson, Leonid V Zingman, Denice M Hodgson-Zingman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4786327?pdf=render

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http://europepmc.org/articles/PMC4786327?pdf=render

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