Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the <i>MTHFR</i> C677T Polymorphism: A Randomized Trial

Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the <i>MTHFR</i> C677T Polymorphism: A Randomized Trial

Methylenetetrahydrofolate reductase (<i>MTHFR</i>) C677T polymorphism associated with body fat accumulation could possibly trigger an inflammatory process by elevating homocysteine levels and increasing cytokine production, causing several diseases. This study aimed to evaluate the effec...

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Bibliographic Details
Main Authors: Jéssica Vanessa de Carvalho Lisboa, Marina Ramalho Ribeiro, Rafaella Cristhine Pordeus Luna, Raquel Patrícia Ataíde Lima, Rayner Anderson Ferreira do Nascimento, Mussara Gomes Cavalcante Alves Monteiro, Keylha Querino de Farias Lima, Carla Patrícia Novaes dos Santos Fechine, Naila Francis Paulo de Oliveira, Darlene Camati Persuhn, Robson Cavalcante Veras, Maria da Conceição Rodrigues Gonçalves, Flávia Emília Leite de Lima Ferreira, Roberto Teixeira Lima, Alexandre Sérgio da Silva, Alcides da Silva Diniz, Aléssio Tony Cavalcanti de Almeida, Ronei Marcos de Moraes, Eliseu Verly Junior, Maria José de Carvalho Costa
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
interleukins
tumor necrosis factor-alpha
dietary intervention
polymorphism
genetic variants
folate
overweight
obesity
Online Access:https://www.mdpi.com/2072-6643/12/2/361

Internet

https://www.mdpi.com/2072-6643/12/2/361

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