ACLY facilitates colon cancer cell metastasis by CTNNB1

ACLY facilitates colon cancer cell metastasis by CTNNB1

Abstract Background Colon cancer is the second leading cancer worldwide. Recurrent disease and chemotherapeutic drug resistance are very common in the advanced stage of colon cancer. ATP-citrate lyase (ACLY), the first-step rate-controlling enzyme in lipid synthesis, is elevated in colon cancer. How...

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Bibliographic Details
Main Authors: Jun Wen, Xuejie Min, Mengqin Shen, Qian Hua, Yuan Han, Li Zhao, Liu Liu, Gang Huang, Jianjun Liu, Xiaoping Zhao
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
ACLY
CTNNB1
Colon cancer
Metastasis
EMT (epithelial-mesenchymal transition)
Online Access:http://link.springer.com/article/10.1186/s13046-019-1391-9

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http://link.springer.com/article/10.1186/s13046-019-1391-9

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