HP1330 Contributes to Streptococcus suis Virulence by Inducing Toll-Like Receptor 2- and ERK1/2-Dependent Pro-inflammatory Responses and Influencing In Vivo S. suis Loads

HP1330 Contributes to Streptococcus suis Virulence by Inducing Toll-Like Receptor 2- and ERK1/2-Dependent Pro-inflammatory Responses and Influencing In Vivo S. suis Loads

Streptococcus suis 2 (SS2) has evolved into a highly invasive pathogen responsible for two large-scale outbreaks of streptococcal toxic shock-like syndrome (STSLS) in China. Excessive inflammation stimulated by SS2 is considered a hallmark of STSLS, even it also plays important roles in other clinic...

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Bibliographic Details
Main Authors: Qiang Zhang, Jingjing Huang, Junping Yu, Zhongmin Xu, Liang Liu, Yajing Song, Xiaomei Sun, Anding Zhang, Meilin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
Streptococcus suis 2
streptococcal toxic shock-like syndrome
excessive inflammation
signaling pathway
recognition receptor
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00869/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00869/full

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