The Effect of Dysfunctional Ubiquitin Enzymes in the Pathogenesis of Most Common Diseases

Ubiquitination is a multi-step enzymatic process that involves the marking of a substrate protein by bonding a ubiquitin and protein for proteolytic degradation mainly via the ubiquitin–proteasome system (UPS). The process is regulated by three main types of enzymes, namely ubiquitin-activating enzy...

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Bibliographic Details
Main Authors: Gizem Celebi, Hale Kesim, Ebru Ozer, Ozlem Kutlu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
E3s
UPS
Online Access:https://www.mdpi.com/1422-0067/21/17/6335