Synthesis of Novel Homo-N-Nucleoside Analogs Composed of a Homo-1,4-Dioxane Sugar Analog and Substituted 1,3,5-Triazine Base Equivalents

Synthesis of Novel Homo-N-Nucleoside Analogs Composed of a Homo-1,4-Dioxane Sugar Analog and Substituted 1,3,5-Triazine Base Equivalents

Enantioselective syntheses from dimethyl tartrate of 1,3,5-triazine homo-N-nucleoside analogs, containing a 1,4-dioxane moiety replacing the sugar unit in natural nucleosides, were accomplished. The triazine heterocycle in the nucleoside analogs was further substituted with combinations of NH2, OH a...

Full description

Bibliographic Details
Main Authors: Qiang Yu, Dirk Schwidom, Per Carlsen, Alexander Exner
Format: Article
Language:English
Published: MDPI AG 2008-12-01
Series:Molecules
Subjects:
1
3
5-Triazine
4-Dioxane
Nucleoside analogue
Heterocycle
Homo-N-nucleoside
Nucleoside analogs
Online Access:http://www.mdpi.com/1420-3049/13/12/3092/

Internet

http://www.mdpi.com/1420-3049/13/12/3092/

Similar Items