Sparsely-connected autoencoder (SCA) for single cell RNAseq data mining

Abstract Single-cell RNA sequencing (scRNAseq) is an essential tool to investigate cellular heterogeneity. Thus, it would be of great interest being able to disclose biological information belonging to cell subpopulations, which can be defined by clustering analysis of scRNAseq data. In this manuscr...

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Bibliographic Details
Main Authors: Luca Alessandri, Francesca Cordero, Marco Beccuti, Nicola Licheri, Maddalena Arigoni, Martina Olivero, Maria Flavia Di Renzo, Anna Sapino, Raffaele Calogero
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-020-00162-6