Redefining the ancestral origins of the interleukin-1 superfamily

The IL-1 evolutionary history is essential in our understanding of function and development. Here the authors use molecular phylogenetic analysis to probe the IL-1 family in a range of species, suggesting disparate phylogenetic association of IL-18 and IL-33 proteins within the IL-1 family.

Bibliographic Details
Main Authors: Jack Rivers-Auty, Michael J. D. Daniels, Isaac Colliver, David L. Robertson, David Brough
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03362-1