Redefining the ancestral origins of the interleukin-1 superfamily

The IL-1 evolutionary history is essential in our understanding of function and development. Here the authors use molecular phylogenetic analysis to probe the IL-1 family in a range of species, suggesting disparate phylogenetic association of IL-18 and IL-33 proteins within the IL-1 family.

Bibliographic Details
Main Authors: Jack Rivers-Auty, Michael J. D. Daniels, Isaac Colliver, David L. Robertson, David Brough
Format: Article
Language:English
Published: Nature Publishing Group 2018-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03362-1
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spelling doaj-041b50750e724afbaab42fdc721cfbdd2021-05-11T10:05:06ZengNature Publishing GroupNature Communications2041-17232018-03-019111210.1038/s41467-018-03362-1Redefining the ancestral origins of the interleukin-1 superfamilyJack Rivers-Auty0Michael J. D. Daniels1Isaac Colliver2David L. Robertson3David Brough4Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill BuildingDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill BuildingDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill BuildingDivision of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Michael Smith BuildingDivision of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, AV Hill BuildingThe IL-1 evolutionary history is essential in our understanding of function and development. Here the authors use molecular phylogenetic analysis to probe the IL-1 family in a range of species, suggesting disparate phylogenetic association of IL-18 and IL-33 proteins within the IL-1 family.https://doi.org/10.1038/s41467-018-03362-1
collection DOAJ
language English
format Article
sources DOAJ
author Jack Rivers-Auty
Michael J. D. Daniels
Isaac Colliver
David L. Robertson
David Brough
spellingShingle Jack Rivers-Auty
Michael J. D. Daniels
Isaac Colliver
David L. Robertson
David Brough
Redefining the ancestral origins of the interleukin-1 superfamily
Nature Communications
author_facet Jack Rivers-Auty
Michael J. D. Daniels
Isaac Colliver
David L. Robertson
David Brough
author_sort Jack Rivers-Auty
title Redefining the ancestral origins of the interleukin-1 superfamily
title_short Redefining the ancestral origins of the interleukin-1 superfamily
title_full Redefining the ancestral origins of the interleukin-1 superfamily
title_fullStr Redefining the ancestral origins of the interleukin-1 superfamily
title_full_unstemmed Redefining the ancestral origins of the interleukin-1 superfamily
title_sort redefining the ancestral origins of the interleukin-1 superfamily
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-03-01
description The IL-1 evolutionary history is essential in our understanding of function and development. Here the authors use molecular phylogenetic analysis to probe the IL-1 family in a range of species, suggesting disparate phylogenetic association of IL-18 and IL-33 proteins within the IL-1 family.
url https://doi.org/10.1038/s41467-018-03362-1
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