Identification of genome-wide nucleotide sites associated with mammalian virulence in influenza A viruses

Identification of genome-wide nucleotide sites associated with mammalian virulence in influenza A viruses

The virulence of influenza viruses is a complex multigenic trait. Previous studies about the virulence determinants of influenza viruses mainly focused on amino acid sites, ignoring the influence of nucleotide mutations. In this study, we collected >200 viral strains from 21 subtypes of influenza...

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Bibliographic Details
Main Authors: Yousong Peng, Wenfei Zhu, Zhaomin Feng, Zhaozhong Zhu, Zheng Zhang, Yongkun Chen, Suli Liu, Aiping Wu, Dayan Wang, Yuelong Shu, Taijiao Jiang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biosafety and Health
Subjects:
Influenza virus
Virulence
Synonymous mutation
Bioinformatics
Computational biology
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053620300215

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http://www.sciencedirect.com/science/article/pii/S2590053620300215

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