LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin.

We have previously identified and characterized the phenomenon of ectopic human centromeres, known as neocentromeres. Human neocentromeres form epigenetically at euchromatic chromosomal sites and are structurally and functionally similar to normal human centromeres. Recent studies have indicated tha...

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Bibliographic Details
Main Authors: Anderly C Chueh, Emma L Northrop, Kate H Brettingham-Moore, K H Andy Choo, Lee H Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2625447?pdf=render