Nuclear exportin receptor CAS regulates the NPI-1-mediated nuclear import of HIV-1 Vpr.

Vpr, an accessory protein of human immunodeficiency virus type 1, is a multifunctional protein that plays an important role in viral replication. We have previously shown that the region between residues 17 and 74 of Vpr (Vpr(N17C74)) contained a bona fide nuclear localization signal and it is targe...

Full description

Bibliographic Details
Main Authors: Eri Takeda, Tomoyuki Murakami, Go Matsuda, Hironobu Murakami, Tamotsu Zako, Mizuo Maeda, Yoko Aida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3218035?pdf=render