Protective effect of metalloporphyrins against cisplatin-induced kidney injury in mice.

Oxidative and nitrative stress is a well-known phenomenon in cisplatin-induced nephrotoxicity. The purpose of this work is to study the role of two metalloporphyrins (FeTMPyP and MnTBAP), water soluble complexes, in cisplatin-induced renal damage and their ability to scavenge peroxynitrite. In cispl...

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Bibliographic Details
Main Authors: Hao Pan, Kezhen Shen, Xueping Wang, Hongzhou Meng, Chaojun Wang, Baiye Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3891880?pdf=render