Osteopontin Promotes Invasion, Migration and Epithelial-Mesenchymal Transition of Human Endometrial Carcinoma Cell HEC-1A Through AKT and ERK1/2 Signaling

Osteopontin Promotes Invasion, Migration and Epithelial-Mesenchymal Transition of Human Endometrial Carcinoma Cell HEC-1A Through AKT and ERK1/2 Signaling

Background/Aims: Osteopontin (OPN) is an Extracellular Matrix (ECM) molecule and is involved in many physiologic and pathologic processes, including cell adhesion, angiogenesis and tumor metastasis. OPN is a well-known multifunctional factor involved in various aspects of cancer progression, includi...

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Bibliographic Details
Main Authors: Yinghua Li, Yunpeng Xie, Dan Cui, Yanni Ma, Linlin Sui, Chenyang Zhu, Hui Kong, Ying Kong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endometrial cancer
Migration
Invasion
EMT
Osteopontin
Online Access:http://www.karger.com/Article/FullText/438518

Internet

http://www.karger.com/Article/FullText/438518

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