Molecular Mechanisms of Resistance to Immune Checkpoint Inhibitors in Melanoma Treatment: An Update

Molecular Mechanisms of Resistance to Immune Checkpoint Inhibitors in Melanoma Treatment: An Update

Over the past decade, immune checkpoint inhibitors (ICI) have revolutionized the treatment of advanced melanoma and ensured significant improvement in overall survival versus chemotherapy. ICI or targeted therapy are now the first line treatment in advanced melanoma, depending on the tumor v-raf mur...

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Bibliographic Details
Main Authors: Sonja Vukadin, Farah Khaznadar, Tomislav Kizivat, Aleksandar Vcev, Martina Smolic
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
melanoma
drug resistance
immune check-point inhibitors
immunotherapy
ipilimumab
pembrolizumab
Online Access:https://www.mdpi.com/2227-9059/9/7/835

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https://www.mdpi.com/2227-9059/9/7/835

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