A Pretraining-Retraining Strategy of Deep Learning Improves Cell-Specific Enhancer Predictions

A Pretraining-Retraining Strategy of Deep Learning Improves Cell-Specific Enhancer Predictions

Deciphering the code of cis-regulatory element (CRE) is one of the core issues of today’s biology. Enhancers are distal CREs and play significant roles in gene transcriptional regulation. Although identifications of enhancer locations across the whole genome [discriminative enhancer predictions (DEP...

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Bibliographic Details
Main Authors: Xiaohui Niu, Kun Yang, Ge Zhang, Zhiquan Yang, Xuehai Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Genetics
Subjects:
deep learning
pretraining
retraining
tissue-specific enhancers
prediction
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01305/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.01305/full

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