Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

Intrinsically disordered proteins (IDPs) can form functional oligomers and in some cases, insoluble disease related aggregates. It is therefore vital to understand processes and mechanisms that control pathway distribution. Divalent cations including Zn<sup>2+</sup> can initiate IDP olig...

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Bibliographic Details
Main Authors: Carolina Cragnell, Lasse Staby, Samuel Lenton, Birthe B. Kragelund, Marie Skepö
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomolecules
Subjects:
Intrinsically disordered proteins
oligomerisation
Histatin
NMR
SAXS
computer simulation
Online Access:https://www.mdpi.com/2218-273X/9/5/168

Internet

https://www.mdpi.com/2218-273X/9/5/168

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