Investigating the Dynamics of MCMV-Specific CD8+ T Cell Responses in Individual Hosts

Investigating the Dynamics of MCMV-Specific CD8+ T Cell Responses in Individual Hosts

Infection by Cytomegalovirus (CMV) is characterized by the massive expansion and continued maintenance of CMV-specific CD8+ T cells for certain CMV-derived peptides. This phenomenon called “memory inflation" has made CMV a primary target for the generation of T cell based vaccine vectors agains...

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Bibliographic Details
Main Authors: Michael Gabel, Nicolas S. Baumann, Annette Oxenius, Frederik Graw
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
CD8+ T cells
MCMV-infection
memory inflation
mathematical modeling
individual dynamics
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01358/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01358/full

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