Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy.

Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy.

Lynch syndrome (LS) is an autosomal dominant condition caused by pathogenic variants in mismatch repair (MMR) genes that predispose individuals to different malignancies, such as colorectal cancer (CRC) and endometrial cancer. Current guidelines recommended testing for LS in individuals with newly d...

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Main Authors: Roberta Pastorino, Michele Basile, Alessia Tognetto, Marco Di Marco, Adriano Grossi, Emanuela Lucci-Cordisco, Franco Scaldaferri, Andrea De Censi, Antonio Federici, Paolo Villari, Maurizio Genuardi, Walter Ricciardi, Stefania Boccia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235038

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https://doi.org/10.1371/journal.pone.0235038

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