Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis

Leptospirosis in humans usually involves hypokalaemia and hypomagnesaemia and the putative mechanism underlying such ionic imbalances may be related to nitric oxide (NO) production. We previously demonstrated the correlation between serum levels of NO and the severity of renal disease in patients wi...

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Main Authors: Cleiton Silva Santos, Everton Cruz de Azevedo, Luciane Marieta Soares, Magda Oliveira Seixas Carvalho, Andreia Carvalho dos Santos, Adenizar Delgado das Chagas Junior, Caroline Luane Rabelo da Silva, Ursula Maira Russo Chagas, Mitermayer Galvao dos Reis, Daniel Abensur Athanazio
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2013-06-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000400438&lng=en&tlng=en