Full genotyping of a highly polymorphic human gene trait by time-resolved fluorescence resonance energy transfer.

The ability of detecting the subtle variations occurring, among different individuals, within specific DNA sequences encompassed in highly polymorphic genes discloses new applications in genomics and diagnostics. DQB1 is a gene of the HLA-II DQ locus of the Human Leukocyte Antigens (HLA) system. The...

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Bibliographic Details
Main Authors: Edoardo Totè, Marco Lamperti, Maria Bondani, Domenico Salerno, Valeria Cassina, Luca Nardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4162610?pdf=render