A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes

A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes

The human genome contains nearly 100 deubiquitinating enzymes (DUBs) responsible for removing ubiquitin moieties from a large variety of substrates. Which DUBs are responsible for targeting which substrates remain mostly unknown. Here we implement the <sup>bio</sup>Ub approach to identif...

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Bibliographic Details
Main Authors: Juanma Ramirez, Gorka Prieto, Anne Olazabal-Herrero, Eva Borràs, Elvira Fernandez-Vigo, Unai Alduntzin, Nerea Osinalde, Javier Beaskoetxea, Benoit Lectez, Kerman Aloria, Jose Antonio Rodriguez, Alberto Paradela, Eduard Sabidó, Javier Muñoz, Fernando Corrales, Jesus M. Arizmendi, Ugo Mayor
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitination
deubiquitinating enzyme
quantitative proteomics
DUBase
Online Access:https://www.mdpi.com/1422-0067/22/9/4851

Internet

https://www.mdpi.com/1422-0067/22/9/4851

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