CAR-T Cell Therapy for the Treatment of ALL: Eradication Conditions and In Silico Experimentation

CAR-T Cell Therapy for the Treatment of ALL: Eradication Conditions and In Silico Experimentation

In this paper, we explore the application of Chimeric Antigen Receptor (CAR) T cell therapy for the treatment of Acute Lymphocytic Leukaemia (ALL) by means of in silico experimentation, mathematical modelling through first-order Ordinary Differential Equations and nonlinear systems theory. By combin...

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Bibliographic Details
Main Authors: Paul A. Valle, Luis N. Coria, Corina Plata, Yolocuauhtli Salazar
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Hemato
Subjects:
acute lymphocytic leukaemia
cancer eradication conditions
CAR-T cell therapy
complete response
in silico
mathematical modelling
Online Access:https://www.mdpi.com/2673-6357/2/3/28

Internet

https://www.mdpi.com/2673-6357/2/3/28

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