Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

Abstract Background Major depressive disorder is a widespread mood disorder. One of the most debilitating symptoms patients often experience is cognitive impairment. Recent findings suggest that inflammation is associated with depression and impaired cognition. Pro-inflammatory cytokines are elevate...

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Bibliographic Details
Main Authors: Ryan J. Worthen, Susan S. Garzon Zighelboim, Camila S. Torres Jaramillo, Eleonore Beurel
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Learned helplessness
Interleukin-10
Learning and memory
Online Access:http://link.springer.com/article/10.1186/s12974-020-01922-1

Internet

http://link.springer.com/article/10.1186/s12974-020-01922-1

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