PCM1 Depletion Inhibits Glioblastoma Cell Ciliogenesis and Increases Cell Death and Sensitivity to Temozolomide

A better understanding of the molecules implicated in the growth and survival of glioblastoma (GBM) cells and their response to temozolomide (TMZ), the standard-of-care chemotherapeutic agent, is necessary for the development of new therapies that would improve the outcome of current GBM treatments....

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Bibliographic Details
Main Authors: Lan B. Hoang-Minh, Loic P. Deleyrolle, Nariaki S. Nakamura, Alexander K. Parker, Regina T. Martuscello, Brent A. Reynolds, Matthew R. Sarkisian
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316300316