TETRALEC, Artificial Tetrameric Lectins: A Tool to Screen Ligand and Pathogen Interactions

TETRALEC, Artificial Tetrameric Lectins: A Tool to Screen Ligand and Pathogen Interactions

C-type lectin receptor (CLR)/carbohydrate recognition occurs through low affinity interactions. Nature compensates that weakness by multivalent display of the lectin carbohydrate recognition domain (CRD) at the cell surface. Mimicking these low affinity interactions <i>in vitro</i> is es...

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Bibliographic Details
Main Authors: Silvia Achilli, João T. Monteiro, Sonia Serna, Sabine Mayer-Lambertz, Michel Thépaut, Aline Le Roy, Christine Ebel, Niels-Christian Reichardt, Bernd Lepenies, Franck Fieschi, Corinne Vivès
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
C-type lectin
DC-SIGNR
glycan array
multivalency
pathogen recognition
Online Access:https://www.mdpi.com/1422-0067/21/15/5290

Internet

https://www.mdpi.com/1422-0067/21/15/5290

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