Computational prediction of vaccine potential epitopes and 3-dimensional structure of XAGE-1b for non-small cell lung cancer immunotherapy

Background: XAGE-1b is shown to be overexpressed in lung adenocarcinoma and to be a strong immunogenic antigen among non-small cell lung cancer (NSCLC) patients. However, 3D structure of XAGE-1b is not available and its confirmation has not been solved yet. Methods: Multiple sequence alignment was r...

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Bibliographic Details
Main Authors: Mohammad M. Tarek, Ayman E. Shafei, Mahmoud A. Ali, Mohamed M. Mansour
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417017300070