MicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic Sclerosis

MicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic Sclerosis

Systemic sclerosis (SSc) is a multisystem fibrotic and autoimmune disease. Both genetic and epigenetic elements mediate SSc pathophysiology. This review summarizes the role of one epigenetic element, known as microRNAs (miRNAs), involved in different signaling pathways of SSc pathogenesis. The expre...

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Bibliographic Details
Main Authors: Yisha Li, Jing Huang, Muyao Guo, Xiaoxia Zuo
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
MicroRNA
Systemic sclerosis
Signaling pathway
TGF-β
Microvascular endothelial cell
Toll-like receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022915001060

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http://www.sciencedirect.com/science/article/pii/S1672022915001060

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