Ultrasound Microbubbles Enhance the Efficacy of Insulin-Like Growth Factor-1 Therapy for the Treatment of Noise-Induced Hearing Loss

Ultrasound Microbubbles Enhance the Efficacy of Insulin-Like Growth Factor-1 Therapy for the Treatment of Noise-Induced Hearing Loss

The application of insulin-like growth factor 1 (IGF-1) to the round window membrane (RWM) is an emerging treatment for inner ear diseases. RWM permeability is the key factor for efficient IGF-1 delivery. Ultrasound microbubbles (USMBs) can increase drug permeation through the RWM. In the present st...

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Bibliographic Details
Main Authors: Yi-Chun Lin, Yuan-Yung Lin, Hsin-Chien Chen, Chao-Yin Kuo, Ai-Ho Liao, Ying-Liang Chou, Chia-Lien Hung, Cheng-Ping Shih, Chih-Hung Wang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
microbubble
ultrasound
inner ear
drug delivery
insulin-like growth factor-1
noise-induced hearing loss
Online Access:https://www.mdpi.com/1420-3049/26/12/3626

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https://www.mdpi.com/1420-3049/26/12/3626

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