Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages

Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages

In inflammation, bacterial products and proinflammatory cytokines induce the formation of large amounts of nitric oxide (NO) by inducible nitric oxide synthase (iNOS), and compounds that...

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Bibliographic Details
Main Authors: Mari Hämäläinen, Riina Nieminen, Pia Vuorela, Marina Heinonen, Eeva Moilanen
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2007/45673

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http://dx.doi.org/10.1155/2007/45673

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