Adaptive Parameter Modulation of Deep Brain Stimulation Based on Improved Supervisory Algorithm

Clinically deployed deep brain stimulation (DBS) for the treatment of Parkinson’s disease operates in an open loop with fixed stimulation parameters, and this may result in high energy consumption and suboptimal therapy. The objective of this manuscript is to establish, through simulation in a compu...

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Bibliographic Details
Main Authors: Yulin Zhu, Jiang Wang, Huiyan Li, Chen Liu, Warren M. Grill
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.750806/full