Astragaloside IV protects neurons from microglia-mediated cell damage through promoting microglia polarization

Astragaloside IV protects neurons from microglia-mediated cell damage through promoting microglia polarization

Astragaloside IV (AST-IV) is a major active ingredient of astragalus, with a neuroprotective effect. The current study is aimed to investigate the impact of AST-IV on the M1/M2 microglial activation in response to lipopolysaccharide (LPS) stimulation, how AST-IV attenuated microglia-mediated neurona...

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Bibliographic Details
Main Authors: Jingwen Yu, Minfang Guo, Yanhua Li, Huiyu Zhang, Zhi Chai, Qing Wang, Yuqing Yan, Jiezhong Yu, Chunyun Liu, Guangxian Zhang, Ma Cungen
Format: Article
Language:English
Published: Termedia Publishing House 2019-06-01
Series:Folia Neuropathologica
Subjects:
astragaloside iv
neuroinflammatory
neurons
microglia polarization
tlr4 intracellular pathways
Online Access:https://www.termedia.pl/Astragaloside-IV-protects-neurons-from-microglia-mediated-cell-damage-through-promoting-microglia-polarization,20,37046,1,1.html

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https://www.termedia.pl/Astragaloside-IV-protects-neurons-from-microglia-mediated-cell-damage-through-promoting-microglia-polarization,20,37046,1,1.html

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