The Inflammasome in Host Defense

Nod-like receptors have emerged as an important family of sensors in host defense. These receptors are expressed in macrophages, dendritic cells and monocytes and play an important role in microbial immunity. Some Nod-like receptors form the inflammasome, a protein complex that activates caspase-1 i...

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Bibliographic Details
Main Authors: Gang Chen, Joao H.F. Pedra
Format: Article
Language:English
Published: MDPI AG 2009-12-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/10/1/97/