Polymorphisms of Catechol-O-Methyl Transferase (COMT) Gene in Vulnerability to Levodopa-Induced Dyskinesia

Purpose. Parkinson's disease (PD), a common neurodegenerative disorder, is usually treated with Levodopa (L-DOPA). The use of this drug, however, is severely limited by the development of side effects of the motor system: Levodopa-induced dyskinesia (LID). The aim of this study is to investiga...

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Main Authors: Svetlana A. Ivanova, Valentina M. Alifirova, Ivan V. Pozhidaev, Maxim B. Freidin, Irina A. Zhukova, Diana Z. Osmanova, Natalia G. Zhukova, Yulia A. Mironova, Vladimir V. Tiguntsev, Olga Yu. Fedorenko, Nikolay A. Bokhan, Bob Wilffert, Anton J.M. Loonen
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2018-08-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29903