NKp46 clusters at the immune synapse and regulates NK cell polarization

NKp46 clusters at the immune synapse and regulates NK cell polarization

Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. The activity of NK cells is tightly regulated by a repertoire of cell-surface expressed inhibitory and activating receptors. NKp46 is a major NK cell activating receptor that is involved in the...

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Bibliographic Details
Main Authors: Uzi eHadad, Timothy J Thauland, Olivia M Martinez, Manish J Butte, Angel ePorgador, Sheri M Krams
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
Cytotoxicity, Immunologic
immune synapse
NKp46
Cellular activation
Cytoskeleton rearrangement
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00495/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00495/full

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