Interleukin-10 inhibits lipopolysaccharide induced miR-155 precursor stability and maturation.

The anti-inflammatory cytokine interleukin-10 (IL-10) is essential for attenuating the inflammatory response, which includes reducing the expression of pro-inflammatory microRNA-155 (miR-155) in lipopolysaccharide (LPS) activated macrophages. miR-155 enhances the expression of pro-inflammatory cytok...

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Bibliographic Details
Main Authors: Sylvia T Cheung, Eva Y So, David Chang, Andrew Ming-Lum, Alice L-F Mui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741136?pdf=render