Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina

Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina

Diseases culminating in photoreceptor loss are a major cause of untreatable blindness. Transplantation of rod photoreceptors is feasible, provided donor cells are at an appropriate stage of development when transplanted. Nevertheless, the proportion of cells that integrate into the recipient outer n...

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Bibliographic Details
Main Authors: R. A. Pearson, A. C. Barber, E. L. West, R. E. Maclaren, Y. Duran, J. W. Bainbridge, J. C. Sowden, R. R. Ali
Format: Article
Language:English
Published: SAGE Publishing 2010-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368909X486057

Internet

https://doi.org/10.3727/096368909X486057

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