PD-1-inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy

PD-1-inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy

The reactivation of human JC polyoma virus (JCPyV) results in lytic infection of oligodendrocytes and neuronal cells. The corresponding clinical picture is called progressive multifocal leukoencephalopathy (PML) and results mostly from a disease-related or drug-induced immunosuppression. The opportu...

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Main Authors: Nora Möhn, Mike P. Wattjes, Ortwin Adams, Sandra Nay, Daria Tkachenko, Friederike Salge, Johanne Heine, Kaweh Pars, Günter Höglinger, Gesine Respondek, Martin Stangel, Thomas Skripuletz, Roland Jacobs, Kurt-Wolfram Sühs
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286421993684

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https://doi.org/10.1177/1756286421993684

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