Regulation of the Bone Marrow Niche by Inflammation

Hematopoietic stem cells (HSC) reside in the bone marrow (BM) within a specialized micro-environment, the HSC niche, which comprises several cellular constituents. These include cells of mesenchymal origin, endothelial cells and HSC progeny, such as megakaryocytes and macrophages. The BM niche and i...

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Bibliographic Details
Main Authors: Ioannis Mitroulis, Lydia Kalafati, Martin Bornhäuser, George Hajishengallis, Triantafyllos Chavakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01540/full