Genome-wide identification of Bcl11b gene targets reveals role in brain-derived neurotrophic factor signaling.

B-cell leukemia/lymphoma 11B (Bcl11b) is a transcription factor showing predominant expression in the striatum. To date, there are no known gene targets of Bcl11b in the nervous system. Here, we define targets for Bcl11b in striatal cells by performing chromatin immunoprecipitation followed by high-...

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Bibliographic Details
Main Authors: Bin Tang, Pietro Di Lena, Lana Schaffer, Steven R Head, Pierre Baldi, Elizabeth A Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3164671?pdf=render