Lipopolysaccharide preconditioning protects hepatocytes from ischemia/reperfusion injury (IRI) through inhibiting ATF4-CHOP pathway in mice.

BACKGROUND: Low-dose lipopolysaccharide (LPS) preconditioning-induced liver protection has been demonstrated during ischemia-reperfusion injury (IRI) in several organs but has not been sufficiently elucidated underlying causal mechanism. This study investigated the role of low-dose LPS preconditioni...

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Bibliographic Details
Main Authors: Jianhua Rao, Jianjie Qin, Xiaofeng Qian, Ling Lu, Ping Wang, Zhengshan Wu, Yuan Zhai, Feng Zhang, Guoqiang Li, Xuehao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3672158?pdf=render